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Results for "

TNF receptor superfamily (TNFRSF)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

CTX-471	Interleukin Related	Inflammation/Immunology Cancer
CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with K_d values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be used for the research of immunomodulation and cancer .

Cat. No.	Product Name	Target	Research Area

HY-P99393

Tavolixizumab MEDI 0562; Tavolimab	Inhibitory Antibodies	Cancer
Tavolixizumab (MEDI 0562; Tavolimab) is a human monoclonal antibody to TNFRSF4 (TNF receptor superfamily member 4) for use in cancer immunology research .

HY-P99178

CTX-471	Interleukin Related	Inflammation/Immunology Cancer
CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with K_d values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be used for the research of immunomodulation and cancer .

Species:	Human (9) Rhesus Macaque (2) Mouse (7) Rat (4) Cynomolgus (1)
Tag:	His (12) Tag Free (1) Avi (2) Fc (10)
Source:	HEK293 (21) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P70516

	TNF RII/TNFRSF1B Protein, Mouse (HEK293, His) Tumor necrosis factor receptor superfamily member 1b; TNFrsf1b; TNF-RII; TNFRII; TNF RII	Mouse	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Mouse (236a.a, HEK293, His) is expressed by HEK293 and has a transmembrane region (V23-G258) with 6*His tag at the C-terminus.

HY-P72443

	TNF RI/TNFRSF1A Protein, Mouse Tumor necrosis factor receptor superfamily member 1A; TNF-R1; CD120a; TNFrsf1a	Mouse	E. coli
	TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNF RI/TNFRSF1A Protein, Mouse is expressed by E. coli and has a transmembrane region (I22-A212).

HY-P73449

	TNF RI/TNFRSF1A Protein, Mouse (HEK293, Fc) Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A	Mouse	HEK293
	TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNF RI/TNFRSF1A Protein, Mouse (HEK293, Fc) is expressed by HEK 293 cells and has a transmembrane region (M1-A212) with a Fc tag at the C-terminus.

HY-P73450

	TNF RI/TNFRSF1A Protein, Mouse (HEK293, His) Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A	Mouse	HEK293
	TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. TNF RI/TNFRSF1A Protein, Mouse (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (M1-A212) with a His tag at the C-terminus.

HY-P72420

	TNF RII/TNFRSF1B Protein, Mouse (HEK293, His-Avi) Tumor necrosis factor receptor superfamily member 1b; TNFrsf1b	Mouse	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Mouse (HEK293, His-Avi) is expressed by HEK293 and has a transmembrane region (V23-G258) with Avi and 6*His tag at the C-terminus.

HY-P70536

	TNF RII/TNFRSF1B Protein, Human (183a.a, HEK293, mFc) TNF-RII; TNFRII; TNF RII; Tumor necrosis factor receptor superfamily member 1B; TNFRSF1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; p75; p80 TNF-alpha receptor; CD120b	Human	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Human (183a.a, HEK293, mFc) is expressed by HEK293 and has a transmembrane region (P24-T206) with mFc tag at the C-terminus.

HY-P74504

	TNFRSF1A Protein, Rat (HEK293, His) Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A	Rat	HEK293
	TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Rat (HEK293, His) is expressed by HEK293 and has a transmembrane region (M1-A211) with a His tag at the C-terminus.

HY-P74505

	TNFRSF1A Protein, Rat (HEK293, Fc) Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A	Rat	HEK293
	TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Rat (HEK293, Fc) is expressed by HEK293 and has a transmembrane region (M1-A211) with a Fc tag at the C-terminus.

HY-P70801

	TNFRSF1A Protein, Human (His) Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; TNFAR; TNFR1	Human	E. coli
	TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Human (His) is expressed by E. coli and has a transmembrane region (I22-T211) with a 6*His tag at the N-terminus.

HY-P76108

	TNF RII/TNFRSF1B Protein, Mouse (HEK293, Fc) TNF-R2; CD120b; Tumor necrosis factor receptor superfamily member 1b; p75; TNFr2	Mouse	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Mouse (HEK293, Fc) is expressed by HEK293 and has a transmembrane region (M1-G258) with Fc tag at the C-terminus.

HY-P75917

	TNFRSF3/LTBR Protein, Rat (HEK293, Fc) Tumor Necrosis Factor receptor superfamily Member 3; TNF-RIII; TNFCR; TNFR3	Rat	HEK293
	TNFRSF3/LTBR Protein, Rat (HEK293, Fc) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Rat (HEK293, Fc) is expressed by HEK293 cells and is a transmembrane protein (M222-W245) with a His tag at the C-terminus.

HY-P75918

	TNFRSF3/LTBR Protein, Rat (HEK293, His) Tumor Necrosis Factor receptor superfamily Member 3; TNF-RIII; TNFCR; TNFR3	Rat	HEK293
	TNFRSF3/LTBR Protein, Rat (HEK293, His) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Rat (HEK293, His) is expressed by HEK293 cells and is a transmembrane protein (M222-W245) with a His tag at the C-terminus.

HY-P77445

	TNFRSF3/LTBR Protein, Cynomolgus (HEK293, Fc) Tumor Necrosis Factor receptor superfamily Member 3; TNF-RIII; TNFCR; TNFR3	Cynomolgus	HEK293
	TNFRSF3/LTBR Protein,Cynomolgus (HEK293, Fc) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Cynomolgus (HEK293, Fc) is expressed by HEK293 cells and is a transmembrane protein (M225-W248) with a His tag at the C-terminus.

HY-P77500

	TNFRH3/TNFRSF26 Protein, Mouse (HEK293, Fc) Tumor necrosis factor receptor superfamily member 26; TNF receptor homolog 3; TNFrh3	Mouse	HEK293
	TNFRH3/TNFRSF26 protein is significantly expressed in the thymus and spleen, indicating that it plays a crucial role in regulating immune system function. Its presence in the thymus, a key organ for T-cell development, underscores its important role in overseeing fundamental cellular processes required for immune maturation. TNFRH3/TNFRSF26 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TNFRH3/TNFRSF26 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TNFRH3/TNFRSF26 Protein, Mouse (HEK293, Fc) is 143 a.a., with molecular weight of ~42.8 KDa.

HY-P72444

	TNF RII/TNFRSF1B Protein, Rhesus Macaque (HEK293, His) TNF-R2; CD120b; Tumor necrosis factor receptor superfamily member 1b; p75; TNFr2	Rhesus Macaque	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Rhesus Macaque (HEK293, His) is expressed by HEK293 and has a transmembrane region (L23-D257) with 6*His tag at the C-terminus.

HY-P77498

	TNF RII/TNFRSF1B Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) TNF-R2; CD120b; Tumor necrosis factor receptor superfamily member 1b; p75; TNFr2	Rhesus Macaque	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is expressed by HEK293 and has a transmembrane region (M1-D257) with hFc tag at the C-terminus.

HY-P70345

	TNFRSF3/LTBR Protein, Human (HEK293, His) rHuTumor necrosis factor receptor superfamily member 3/TNFRSF3, His; Tumor Necrosis Factor receptor superfamily Member 3; Lymphotoxin-Beta receptor; Tumor Necrosis Factor C receptor; Tumor Necrosis Factor receptor 2-Related Protein; Tumor Necrosis Factor receptor Type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3	Human	HEK293
	TNFRSF3/LTBR Protein, Human (HEK293, His) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Human (HEK293, His) is expressed by HEK293 cells and is a transmembrane protein (L228-W248) with a His tag at the C-terminus.

HY-P700263

	TNFR-1/CD120a Protein, Human (HEK293, His) Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A	Human	HEK293
	The TNFR-1/CD120a protein is a receptor for TNFSF2/TNF-α and TNFSF1/lymphotoxin-α, and initiates caspase-8-mediated apoptosis upon TNF binding. It induces non-cytocidal TNF action, activates acid sphingomyelinase and establishes an antiviral state. TNFR-1/CD120a Protein, Human (HEK293, His) is the recombinant human-derived TNFR-1/CD120a protein, expressed by HEK293 , with C-8*His labeled tag. The total length of TNFR-1/CD120a Protein, Human (HEK293, His) is 182 a.a., with molecular weight of 28-38 kDa.

HY-P700264

	TNFR-1/CD120a Protein, Human (HEK293, Fc) Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A	Human	HEK293
	The TNFR-1/CD120a protein is a receptor for TNFSF2/TNF-α and TNFSF1/lymphotoxin-α, and initiates caspase-8-mediated apoptosis upon TNF binding. It induces non-cytocidal TNF action, activates acid sphingomyelinase and establishes an antiviral state. TNFR-1/CD120a Protein, Human (HEK293, Fc) is the recombinant human-derived TNFR-1/CD120a protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TNFR-1/CD120a Protein, Human (HEK293, Fc) is 182 a.a., with molecular weight of 55-70 kDa.

HY-P70806

	TRAIL R2/TNFRSF10B Protein, Human (127a.a, HEK293, His) Tumor Necrosis Factor receptor superfamily Member 10B; Death receptor 5; TNF-Related Apoptosis-Inducing Ligand receptor 2; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9	Human	HEK293
	TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and recruits caspase-8 through FADD to initiate cell apoptosis. It forms the death-inducing signaling complex (DISC), activates caspases and mediates apoptosis. TRAIL R2/TNFRSF10B Protein, Human (127a.a, HEK293, His) is the recombinant human-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TRAIL R2/TNFRSF10B Protein, Human (127a.a, HEK293, His) is 127 a.a., with molecular weight of ~18.0 kDa.

HY-P72806

	TNFRSF3/LTBR Protein, Human (HEK293, Fc) Tumor Necrosis Factor receptor superfamily Member 3; Lymphotoxin-Beta receptor; Tumor Necrosis Factor C receptor; Tumor Necrosis Factor receptor 2-Related Protein; Tumor Necrosis Factor receptor Type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3	Human	HEK293
	TNFRSF3/LTBR Protein, Human (HEK293, Fc) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Human (HEK293, Fc) is expressed by HEK293 cells and is a transmembrane protein (L228-W248) with a Fc tag at the C-terminus.

HY-P70815

	TNFRSF10C Protein, Human (HEK293, His) Tumor Necrosis Factor receptor superfamily Member 10C; Antagonist Decoy receptor for TRAIL/Apo-2L; Decoy TRAIL receptor Without Death Domain; Decoy receptor 1; DcR1; Lymphocyte Inhibitor of TRAIL; TNF-Related Apoptosis-Inducing Ligand receptor 3; TRAIL receptor	Human	HEK293
	The TNFRSF10C protein is a receptor for TRAIL and lacks a cytoplasmic death domain, making it unable to induce apoptosis. Instead, it protects cells by competing for ligand binding with TRAIL-R1 and R2, acting as a decoy receptor and mitigating TRAIL-mediated apoptosis. TNFRSF10C Protein, Human (HEK293, His) is the recombinant human-derived TNFRSF10C protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TNFRSF10C Protein, Human (HEK293, His) is 196 a.a., with molecular weight of 50-60 kDa.

HY-P78091

	CD40 Protein, Human (Biotinylated, HEK293, His-Avi) CD40; CD40L receptor; TNFRSF5; B cell surface antigen CD40; B-cell surface antigen CD40; Bp50B cell-associated molecule; CD40 antigen; CD40 molecule, TNF receptor superfamily member 5; CD40 type II isoform; CDw40; MGC9013; nerve growth factor receptor-relat	Human	HEK293
	CD40 protein is a TNFSF5/CD40LG receptor that transduces signals through TRAF6 and MAP3K8-mediated pathways, activates ERK in macrophages and B cells, and induces immunoglobulin secretion. CD40 exists as monomers and homodimers and interacts with TRAF proteins (TRAF1, TRAF2, TRAF3, TRAF5, and TRAF6). CD40 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD40 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD40 Protein, Human (Biotinylated, HEK293, His-Avi) is 173 a.a., with molecular weight of 35-40 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P82843

DcR2 Antibody (YA2588) TNFRSF10D; DCR2; TRAILR4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain; CD	WB, IHC-P, ICC/IF	Human

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